Opioid Antitussive Quantity Limits and Opioid Quantity Limits

Opioid Antitussive Quantity Limits

Effective January 1, 2019, HMSA will be placing quantity limits on opioid antitussive products to ensure member safety and appropriate use. Quantity limits are based on product labeling, FDA guidance, standards of medical practice, evidence-based drug information, and published guidelines. These quantity limits will apply to HMSA Commercial formularies (Select, Choice, Essential, Metallic and Optimal) and QUEST Integration.

ALL opioid antitussives will have an Age Limit of 18 year or older.

MedicationStrengthQuantity Limit
hydrocodone bitartrate/guaifenesin tab5-400 mg6 tablets/day
hydrocodone w/ homatropine tab5-1.5 mg6 tablets/day
hydrocodone w/ homatropine syrup5-1.5 mg/5ml30 ml/day
codeine polist-chlorphen polist er susp (Tuzistra Xr)14.7-2.8 mg/5ml20 ml/day
chlorpheniramine w/ codeine liquid (Codar Ar )2-8 mg/5ml60 ml/day
chlorpheniramine w/ codeine liquid (Z-Tuss Ac)2-9 mg/5ml60 ml/day
promethazine w/ codeine syrup6.25-10 mg/5ml30 ml/day
hydrocod polst-chlorphen polst cap er (Tussicaps)12hr 5-4 mg2 capsules/day
hydrocod polst-chlorphen polst cap er (Tussicaps)12hr 10-8 mg2 capsules/day
hydrocod polst-chlorphen polst er susp10-8 mg/5ml10 ml/day
codeine-pyrilamine syrup (Pro-Clear Ac)9-8.33 mg/5ml60 ml/day
promethazine-phenylephrine-codeine syrup6.25-5-10 mg/5ml30 ml/day
phenylephrine-bromphen w/ codeine liquid (M-End Pe )3.33-1.33-6.33 mg/5ml90 ml/day
phenylephrine-chlorphen w/ codeine syrup (Capcof )5-2-10 mg/5ml60 ml/day
pseudoephedrine-bromphen-codeine liquid (Rydex)10-1.33-6.33 mg/5ml90 ml/day
pseudoephedrine-bromphen-codeine liquid (Mar-Cof Bp )30-2-7.5 mg/5ml60 ml/day
pseudoeph-chlorphen w/ hydrocodone soln60-4-5 mg/5ml30 ml/day

* This is a list of quantity limits for reference regarding opioid antitussive medications. It does not imply it is a formulary agent. Refer to applicable formulary document for formulary status.

Opioid Quantity Limits

Effective July 1, 2018, HMSA will be placing quantity limits on ALL opioid products to ensure member safety and appropriate use. Quantity limits are based on product labeling, FDA guidance, standards of medical practice, evidence-based drug information, and published guidelines. Quantity limits will not be placed on drugs used for medication-assisted treatment. The following quantity limits are new or are changing effective July 1, 2018. Additional quantity limits and a link to a comprehensive list of quantity limits for opioids will be included in the May 2018 edition of Health Pro News. These limits will apply to ALL HMSA Commercial formularies.

MedicationStrengthQuantity Limit
ascomp/cod cap 30mg50-325-40-30 mg12 capsules per day
aspirin-caffeine-dihydrocodeine cap356.4-30-16 mg336 capsules per month
butalbital-acetaminophen tab50-300 mg12 tablets per day
butalbital-acetaminophen tab50-325 mg12 tablets per day
butalbital-acetaminophen-caffeine cap50-300-40 mg13 capsules per day
butalbital-acetaminophen-caffeine cap50-325-40 mg12 capsules per day
butalbital-acetaminophen-caffeine tab50-325-40 mg12 tablets per day
butalbital-acetaminophen-caffeine w/ codeine cap50-300-40-30mg13 capsules per day
butalbital-acetaminophen-caffeine w/ codeine cap50-325-40-30 mg12 capsules per day
butalbital-aspirin-caffeine cap50-325-40 mg12 capsules per day
butalbital-aspirin-caffeine w/ codeine50-325-40-30 mg12 capsules per day
butorphanol tartrate spray10mg/ml (2.5ml)2 bottles per month
codeine sulfate15 mg24 tablets per day
codeine sulfate30 mg12 tablets per day
codeine sulfate60 mg6 tablets per day
fentanyl td (Duragesic)All strengths1 patch every 3 days
hydrocodone- acetaminophen (Hycet Soln)7.5-325 mg per 15ml184 ml per day
hydrocodone- acetaminophen (Lortab Elixir)10-300 mg per 15ml67.5 ml per day
hydrocodone- acetaminophen (Norco)10-325 mg369 tablets per month
hydrocodone- acetaminophen (Norco)5-325 mg369 tablets per month
hydrocodone- acetaminophen (Norco)7.5-325 mg369 tablets per month
hydrocodone- acetaminophen (Xodol)5-300mg12 tablets per day
hydrocodone- acetaminophen (Xodol)7.5-300 mg6 tablets per day
hydrocodone- acetaminophen (Xodol)10-300 mg6 tablets per day
hydrocodone bitartrate Er (Zohydro ER)10 mg4 capsules per day
hydrocodone bitartrate Er (Zohydro ER)15 mg4 capsules per day
hydrocodone bitartrate Er (Zohydro ER)20 mg4 capsules per day
hydrocodone bitartrate Er (Zohydro ER)30 mg2 capsules per day
hydrocodone bitartrate Er (Zohydro ER)40 mg2 capsules per day
hydrocodone bitartrate Er (Zohydro ER)50 mg2 capsules per day
hydrocodone bitartrate ER (Hysingla ER)All strengths1 tablet per day
hydrocodone-ibuprofenAll strengths6 tablets per day
hydromorphone ERAll strengths1 tablet per day
hydromorphone hcl supp3 mg4 suppositories per day
hydromorphone hcl tabs2 mg12 tablets per day
hydromorphone hcl tabs4 mg6 tablets per day
hydromorphone hcl tabs8 mg6 tablets per day
levorphanol2 mg120 tablets per month
meperidine hcl50mg24 tablets per month
meperidine hcl100 mg12 tablets per month
morphine sulfate beads cap ERAll strengths1 capsule per day
morphine sulfate ERAll strengths3 tablets per day
morphine sulfate soln10 mg/5ml1800 ml per month
morphine sulfate soln2 0mg/5ml900 ml per month
morphine sulfate soln100 mg/5ml180 ml per month
morphine sulfate tablet15 mg180 tablets per month
morphine sulfate tablet30 mg180 tablets per month
opium tincture deodorized10mg/ml120 ml per month
oxycodone hcl5 mg360 tablets per month
oxycodone hcl10 mg180 tablets per month
oxycodone hcl15 mg180 tablets per month
oxycodone hcl20 mg180 tablets per month
oxycodone hcl30 mg180 tablets per month
oxycodone hcl tab ER 12hr deterAll strengths3 tablets per day
oxymorphone ER (Opana ER)All strengths4 tablets per day
oxymorphone hcl5 mg360 tablets per month
oxymorphone hcl10 mg360 tablets per month
oxymorphone hcl ERAll strengths2 tablets per day
pentazocine/naloxone50 mg/0.5mg360 tablets per month
tapentadol (Nucynta)50 mg12 tablets per day
tapentadol (Nucynta)75 mg8 tablets per day
tapentadol (Nucynta)100 mg6 tablets per day
tapentadol ER (Nucynta ER)50 mg10 tablets per day
tapentadol ER (Nucynta ER)100 mg5 tablets day
tapentadol ER (Nucynta ER)150 mg3 tablets per day
tapentadol ER (Nucynta ER)200 mg2 tablets per day
tapentadol ER (Nucynta ER)250 mg2 tablets per day
tramadol hcl50 mg240 tablets per month
tramadol hcl ER cap100 mg3 tablets per day
tramadol hcl ER cap150 mg2 tablets per day
tramadol hcl ER cap200 mg2 tablets per day
tramadol hcl ER cap300 mg1 tablet per day
tramadol hcl ER tab100 mg3 tablets per day
tramadol hcl ER tab200 mg2 tablets per day
tramadol hcl ER tab300 mg1 tablet per day
tramadol/acetaminophen37.5-325 mg40 tablets per month

Revision History

Date Nature of Revision
08/03/2026 Migrated to new platform.