Intravenous Immune Globulin (IVIG) Therapy – Administrative Information – IV Therapy Index

Claims Filing and Payment Criteria

Please use the codes listed below when submitting claims for IVIG therapy:

Code Description
S9338 Home infusion therapy, immunotherapy, administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem
CPT Code Description
99601 Home infusion/specialty drug administration, per visit (up to two hours)
HCPCS Code Description
J3590 Identify each drug using the NDC number

Example

The patient is receiving treatment for thrombocytopenic purpura. The attending physician has prescribed 25 grams of Iveegam EN daily for five days each month.

The provider bills the per diem charge for five days of IVIG therapy on the first service line.

S9338 x 5 units

The Iveegam EN comes prepackaged in 5-g vials for reconstitution. To obtain the required 25 grams a day, the provider will use five 5-g vials. In five days, the patient will have used 25 of the 5-g vials. These figures should appear in the “days or units” column (24G) of the CMS 1500 claim form.

J3590 NDC: 64193-0250-50 x 25 units

A precertification number appears in block 23 of the CMS 1500 claim form. The number indicates that IVIG therapy was approved.

Nursing Services

Nursing services (CPT codes 99601 and 99602) are covered and do not require precertification. Nursing services may be billed separately and are not included in the per diem for IV therapy.


Revision History

Date Nature of Revision
08/03/2026 Migrated to new platform.