Depression

Clinical practice guidelines serve as an educational reference, and do not supersede the clinical judgment of the treating physician with respect to appropriate and necessary care for an individual patient. In the event that HMSA policies differ from the clinical practice guidelines, for benefit purposes, HMSA policies shall supersede the clinical practice guidelines.

The links below direct you to the latest national guidelines (in alphabetic order):

  • American Academy of Pediatrics

    Guidelines for Adolescent Depression in Primary Care (GLAD-PC): Part II. Treatment and Ongoing Management

    Amy H. Cheung, MD, Rachel A. Zuckerbrot, MD, Peter S. Jensen, MD, Danielle Laraque, MD, Ruth E.K. Stein, MD, e GLAD-PC STEERING GROUP

  • American College of Physicians

    Nonpharmacologic and Pharmacologic Treatments of Adult Patients with Major Depressive Disorder: A Systematic Review and Network Meta-analysis for a Clinical Guideline by the American College of Physicians (2023)

  • American Psychological Association [PDF]

    The American Psychological Association developed this clinical practice guideline to provide recommendations for the treatment of depressive disorders (including major depression, subsyndromal depression, and persistent depressive disorder). It addresses three developmental cohorts: children and adolescents; general adults; and older adults (ages 60 and over).

  • U.S. Preventive Services Task Force (USPSTF)

    A link to USPS Task Force 2022 recommendations for Depression and Suicide Risk in Children and Adolescents: Screening

  • U.S. Preventive Services Task Force (USPSTF)

    A link to to USPS Task Force 2023 recommendations for Depression and Suicide Risk in Adults: Screening

  • VA/DoD CPG – Management of Major Depressive Disorder (MDD) (2022)

    Describes critical decision points in the management of Major Depressive Disorder

Guideline Review Date: December 2025

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Revision History

Date Nature of Revision
08/03/2026

Migrated to new platform.